ISSN: 2249–9504
CAS CODEN: IJPCDX

THE NEW TRANSITION METAL COMPLEXES OF N,N?-(PIPERAZINE1,4 DIBIS((PHENYLMETHYLENE)) DIACETAMIDE AND THEIR BIOLOGICAL ACTIVITY

Abstract

Author(s): K. Babu and P. Pitchai*

We synthesized new mannich base N,N’-(piperazine-1,4-dibis((phenyl)methylene)) diacetamide. and their transition metal complexes and the structure of ligand and complexes deduced with help of UV-Vis, IR, 1HNMR, 13CNMR spectra and their physical data such as melting point, magnetic susceptibility, molar conductance. Antibacterial activity of newly synthesized compounds was examined against selective bacteria such as E. coli, P. aureoginosa (gram negative) S. aureus, staphylococcus epidermidis (gram positive) and antifungal activity against C. albicans and A. niger by disc diffusion method. The transition metal complexes showed good antibacterial and antifungal activity than the free ligand was observed.

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