ISSN: 2249-9504
CAS CODEN: IJPCDX

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Citations : 3566

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International Journal of Pharmaceutical, Chemical and Biological Sciences peer review process verified at publons

SYNTHESIS, SPECTRAL CHARACTERIZATION AND ANTIOXIDANT ACTIVITIES OF3'-METHYL-2',6'-DIPHENYL-1,3-DIHYDROSPIRO[BENZO[D]IMIDAZOLE-2,4'-PIPERIDINE]

Abstract

Author(s): Elanchezhian Balachandravinayagam*,Manivannan Natarajan and Selvanathan Ganesan

3'-methyl-2',6'-diphenyl-1,3-dihydrospiro[benzo[d]imidazole-2,4'-piperidine]was synthesized by condensing 3-methyl-2,6-diarylpiperidin-4-one with o-phenylenediamine. The synthesized compound was characterized by IR, Mass and NMR spectral studies. NMR spectral assignments are made clearly by their one-dimensional (1H and 13C NMR) and two-dimensional (HOMO COSY and NOESY) NMR spectra. The spectral data suggest that the compound adopt chair conformation with equatorial orientation of all the substituents. The target compound exhibited an excellent free radical scavenging activity on the stable DPPH free radical (88.8 %).

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