ISSN: 2249-9504
CAS CODEN: IJPCDX

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Citations : 3566

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SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF METAL (II) COMPLEXES WITH SCHIFF BASE DERIVED FROM PROPIONALDEHYDE WITH ANILINE

Abstract

Author(s): IM. Wakil1* , MB. Abubakar2, GA. Mala3, S. Hassan4, A. Abubakar1 and I. Waziri3

Complexes of Mn(II), Cu(II) and Ni(II) with Schiff base ligand (HL) derived from condensation of propionaldehyde with aniline were synthesized in ethanolic medium. The complexes were characterized on the basis of melting point, conductivity, solubility, IR and UV/Visible spectral studies. The in-vitro antibacterial activities of the complexes were tested against different strains of bacteria such as Gram positive (Staphylococcus aureus, Streptococcus pyogenes), Gram negative (Escherichia coli, Salmonella typhi) and fungus Candida albicans. The complexes formed in moderate yields (36-66%) and they are of various colors, ranging from buff to brown and black. The IR spectral data revealed that the complexes coordinated through azomethine nitrogen and phenolic oxygen of the ligands. Further conclusive evidence of the coordination of the Schiff base with the metal ions was shown by the appearance of new bands due to v(M-N) and v(M-O) in the metal complexes. The UV/visible electronic spectra further revealed that Mn(II), Cu(II) and Ni(II) complexes are octahedral. Measured molar conductance (100.50 x 10-3 - 177.00 x 10-3 ) showed that the complexes are non-electrolytes. The results of the anti-microbial study showed that the complexes had more potent activities than their free ligands.

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