ISSN: 2249–9504
CAS CODEN: IJPCDX

SYNTHESIS, CHARACTERIZATION AND ANTIFUNGAL ACTIVITY OF BENZIMIDAZOLE CONTAINING CHALCONE DERIVATIVES

Abstract

Author(s): Priya B Rajput*, Shraddha A Phadke and Priyanka V Bandiwadekar

Derivatives of 2-acetylated benzimidazole chalcone’s posses pharmacological action. A series of 2-
substituted benzimidazole Chalcone derivatives were synthesized and were characterized by IR and
1H NMR spectroscopy. All these synthesized compounds were tested for their Antifungal activity
against C.albicans (MTCC 227) in polar solvent DMSO. Among the screened compounds, SP3
containing bromine group as substituent exhibited most potent antifungal activity.

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