ISSN: 2249-9504

Synthesis and characterization of some 3-(2-(5-phenyl-1H-1,2,3-triazol-1-yl)acetyl)-2H-chromen-2-ones, using Click reaction


Author(s): Jayendra Kanzariya, Prachi Trivedi, Sanjay Hadiyal, Ashish Dhamshaniya, Shahrukhkhan Safi and Jatin Upadhyay

Novel 1,2,3-triazoles were synthesised using the one-pot reaction of, 3-(2-azidoacetyl)-2H-chromen2-one and terminal alkynes in the presence of water: t-BuOH: DMF(1:1:1) using the click approach, The new therapeutically active 1,2,3, triazole compounds have been synthesised bearing coumarin moiety The structures of compounds have been confirmed by various spectroscopic methods

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