ISSN: 2249–9504
CAS CODEN: IJPCDX

SYNTHESIS AND CHARACTERIZATION OF ANTICANCER DRUGS BASED ON PLATINUM

Abstract

Author(s): Ali Nemati Kharat*, Bahareh Tamaddoni Jahromi , Ehsan Mohammadifar and Jaleh Zareyi

Platinum(II) complexes, oxaliplatin and carboplatin, have been prepared and characterized. In the case of carboplatin, 1,3-Cyclobutanedicarboxylic ligand have been synthesized in good yields using different methodology to achieve high purity. 1H and 13C NMR spectra, IR spectroscopy were used to characterize this compound. The carboplatin complex was achieved with high purity confirmed by high-performance liquid chromatography (HPLC).

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