ISSN: 2249-9504
CAS CODEN: IJPCDX

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Citations : 3566

International Journal of Pharmaceutical, Chemical and Biological Sciences received 3566 citations as per google scholar report

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SCREENING OF PHYTO-CHEMICAL CONSTITUENTS, TRACE METAL CONCENTRATIONS AND ANTIMICROBIAL EFFICIENCY OF RAUVOLFIA TETRAPHYLLA

Abstract

Author(s): VS. Nandhini and G. Vijistella Bai*

Phytochemical constituents and trace metals concentrations, and antimicrobial activity of ethanolic extract of Rauvolfia tetraphylla leaves were investigated. The phytochemical screening of the crude extract revealed the presence of steroids, reducing sugars, sugars, alkaloids, flavonoids, saponins, tannins and amino acids. The leave powder was subjected to analyze the trace metals using atomic absorption spectroscopy (AAS). The average concentrations of Cd, Cr, Cu, Fe, Ni, Pb and Zn were BDL, 0.03, 0.2, 0.5, BDL, 0.06 and 0.5 mg kg-1 , respectively. And also the crude ethanol extract of Rauvolfia tetraphylla were analyzed for in-vitro antimicrobial activity against certain pathogens and the zone of inhibition were compared with control drug Methicillin and Itraconazole. The Salmonella typhimurium is the most sensitive strains (17mm) to test solution while smallest inhibition were recorded in Micrococcus luteus and Cryptococcus sp. (11 mm).

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