ISSN: 2249-9504
CAS CODEN: IJPCDX

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Citations : 3566

International Journal of Pharmaceutical, Chemical and Biological Sciences received 3566 citations as per google scholar report

International Journal of Pharmaceutical, Chemical and Biological Sciences peer review process verified at publons

PROXIMATE ANALYSIS, PHYTO-CHEMICAL SCREENING AND ANTI-INFLAMMATORY ACTIVITY OFCOCCINIAINDICA

Abstract

Author(s): AritraChatterjeeand SumanaChatterjee

Coccinia indica, an annual creeper, is available all over India. In the present investigation, petroleum ether extract, 60% methanolic extract and aqueous extracts of the whole plant were made using hot extraction procedure using soxhlet apparatus. The qualitative phyto-chemical screening procedure was performed on each extract. Phyto-chemical study reveals that flavonoid was only present in the methanolic extract. The anti-inflammatory activity of each extract and that of a standard drug, diclofenac sodium were studied using Carageenan induced rat paw oedema model. The extracts and the standard drug were administered orally.It was observed that 60%methanolic extract of Coccinia indicaproduced maximum anti-inflammatory activity even more than the standard drug, diclofenac sodium after 3 hours. Petroleum ether extract and the aqueous extract produced less percentage of inhibition in comparison the standard drug.

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