ISSN: 2249–9504
CAS CODEN: IJPCDX

PRELIMINARY PHYTOCHEMICAL ANALYSIS AND IN VITRO ANTHELMINTIC ACTIVITY OF MILLINGTONIA HORTENSIS LINN

Abstract

Author(s): DS. Chumbhale1*, SR. Chaudhari1 and CD Upasani2

The present study was designed to evaluate the anthelmintic potential of Millingtonia hortensis Linn. (M. hortensis) is an important medicinal tree in Indian traditional system of medicine. In this study, the various extract of stems of M. hortensis was investigated for their anthelmintic activity against the earthworms, Pheritima posthuma. Each extract was studied in the bioassay at 20 mg/ml, which involved determination of time of paralysis and time of death of the worms. The stems extracts of plant, M. hortensis showed significant activity against worms and exhibited considerable anthelmintic activity. Albendazole (20 mg/ml) and distilled water were included in the assay as a standard reference drug and control respectively. Present investigation indicated that among the various extract, ethyl acetate soluble fraction of methanolic extracts of plant, M. hortensis showed more prominent activity. These findings will be useful toward the better acceptability of this plant in therapeutics.

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