Author(s): Kharat Amol*andPawar Pratibha
Novel drug delivery system isa novel approach to drug delivery that addresses the limitations of the traditional drug delivery systems. Our country has a vast knowledge base of Ayurveda whose potential is only being realized in the recent years. If the novel drug delivery technology is applied in herbal medicine, it may help in increasing the efficacy and reducing the side effects of various herbal compounds and herbs.Development as novel formulations owing to lack of scientific justification andprocessing difficulties, such as standardization, extraction and identification of individual drug components in complex polyhedral systems. Determination of pharmacokinetics, mechanism of action, site of action, accurate dose required etc.) Of herbal medicines to be incorporated in novel drug delivery system, such as nanoparticles, microemulsions, matrix systems, solid dispersions, liposome, solid lipid nanoparticles and so on. The method by which a drug is delivered can have a significant effect on its efficacy. Some drugs have an optimum concentration range within which maximum benefit is derived, and concentrations above or below this range can be toxic or produce no therapeutic benefit at all.Many herbal compounds including quercetin, genistein, naringin, sinomenine, piperine, glycyrrhizin and nitrile glycoside have demonstrated capability to enhance the bioavailability.