ISSN: 2249-9504
CAS CODEN: IJPCDX

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Citations : 3566

International Journal of Pharmaceutical, Chemical and Biological Sciences received 3566 citations as per google scholar report

International Journal of Pharmaceutical, Chemical and Biological Sciences peer review process verified at publons

METHOD DEVELOPMENT AND VALIDATION OF CIS-BROMOBENZOATE BY RP-HPLC IN PURE AND PHARMACEUTICAL DOSAGE FORM

Abstract

Author(s): N. Chittemma and M. Manimala

ABSTRACT The aim of the study was to develop and validate RP-HPLC method for the analysis of cisbromobenzoate in marketed tablets and pure form.The methods was validated in terms of system sutiability,linearity, accuracy (%Recovery), precision (system precision& intermediate precision), speficity,ruggedness ,and robustness. The method found to be linear (R2 =0.999) and accurate. The methods was also found precise (% RSD< 2%) and robust. All validation parameters were within the acceptable range as per International Conference on Harmonization (ICH). Parameters of validation prove the precision of the method and its applicability for the determination of cisbromobenzoate in pharmaceutical tablet formulations.

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