ISSN: 2249–9504
CAS CODEN: IJPCDX

MEDICATED TRANSDERMAL THERAPEUTIC SYSTEMS: AN UPDATED OVERVIEW

Abstract

Author(s): Mithilesh Sahu, Mithun Bhowmick, Rajesh Kushwaha and Jagdish Rathi

The Discovery of Transdermal Drug Delivery System (TDDS) is a breakthrough in the field of controlled drug delivery systems. A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a time released dose of medication systemically for treating illnesses. The ability of TDDS to deliver drugs for systemic effect through intact skin while bypassing first pass metabolism has accelerated transdermal drug delivery research in the field of pharmaceutics. The skin as a route for systemic drug administration has become very attractive since the introduction of transdermal therapeutic systems in the form of patches. An essential prerequisite for the development of TDDS is that the drug must be capable of passing through skin at a sufficiently high rate to achieve therapeutic plasma concentrations. Over a decade of such extensive research activities, many transdermal patches have been developed and successfully commercialized

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