ISSN: 2249–9504
CAS CODEN: IJPCDX

INTRAVESICAL DRUG DELIVERY SYSTEM FOR BLADDER: AN OVERVIEW

Abstract

Author(s): Kishor Butte*, Munira Momin, Suvarna KurhadeandSwapan Kar

The current aspect of any novel drug delivery system is to deliver a drug to specific site for better pharmacological effect as well as bettercontrol over the disease condition. The site specificity which demands more attention is brain, spinal and other localised sites like, bladder. The targeted drug delivery to cancerous cell of different organs of the body has reached to its molecular level. The attempt has been made in this review to give an insight into the treatment of genitourinary condition. These conditions require very large dose of medication due to poor absorption and loss of drug due to metabolism. The local effect of drug can be achieved using intravesicular drug delivery system. The physiology of the biological barriers, i.e. urothelium of bladder poses major challenge in the development of intravesicular drug delivery system. This review is prepared with an intension to address all these issue in detail and approaches to overcome barrier for drug delivery to bladder. The role of nanotechnology leads to minimal invasive procedure for bladder, prostate and other surrounding organs for more precise drug delivery has also been discussed in detail

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