ISSN: 2249–9504
CAS CODEN: IJPCDX

ESTIMATION OF WNT BETACATENIN LEVELS IN GENERALIZED CHRONIC AND AGGRESSIVE PERIODONTITIS-A COMPARATIVE CROSS SECTIONAL HISTOCHEMICAL STUDY

Abstract

Author(s): Waseem Ahmed Kazi1* , Shivaraj B Warad2, Syed Manazir Hussain3, P. Prasanna Kumar4, S. Mohamed Shahid5, Mohammed Yasin Soudagar6 and BS. Sridhar7

Periodontitis is a chronic inflammatory disease characterized by the enhanced expression of inflammatory mediators leading to alveolar bone resorption.1 Although, oral bacterial infection is a major factor of Periodontitis, its progression and severity depends upon interplay between genetic and environmental factors. . Periodontopathic bacteria produce many virulence factors, such as lipopolysaccharide(LPS) including the production of inflammatory cytokines which leads to the stimulation of host cells, thus playing an important role in mediating and controlling cellular interactions.

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