ISSN: 2249-9504
CAS CODEN: IJPCDX

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Citations : 3566

International Journal of Pharmaceutical, Chemical and Biological Sciences received 3566 citations as per google scholar report

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EFFECT OF THYROXINE ON LDL AND TOTAL CHOLESTEROL IN HYPOTHYROID PATIENTS

Abstract

Author(s): Nimmy. N. John, MP. Narmadha, KM. Binu

ABSTRACT The study was carried out to assess the effect of l- thyroxine on low density lipoprotein(LDL), high density cholesterol(HDL) and total cholesterol(TC) in hypothyroid patients. 50 patients who were newly diagnosed with hypothyroidism and on treatment with thyroxine was taken for the study. Patient’s demographic details, family history, symptoms experienced and laboratory investigation of TSH (Thyroid stimulating hormone), T3 (Triiodothyroxine), T4(Tetraiodothyronine) levels were collected and this were analysed by descriptive statistics methods. The study reveals that in case of hypothyroidism patients having age group below 45 years an increase in weight and increase in cholesterol level is observed. It is also observed that lower limits of TSH during the course of treatment and improvement in T3 and T4 levels in hypothyroid patients of the same age group. This detailed study of the investigations indicate that the normal level of TSH,T3,T4 and cholesterol level at the end of 3rd month and hence it can be concluded that the regular treatment with l- thyroxine for a period of 1 year may help to attain the normal levels.

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