Author(s): Wansi SL1*,TchumbiepNgoune GL1, NguelefackTB1, WaboPone J1, NyadjeuP2,KueteFofieC1and KamanyiA1
The aim of this study was to investigate the effect of the excessive intake of fresh palm oil and refined palm oil (PROMOR) on some physiological parameters such as growth rate, lipid profile and arterial blood pressure in rats. Three groups of Wistar albino rats were submitted to different types of diets rich in fresh palmoil (FPO) or in refined palm oil (RPO) at the doses of 10%, 15% and 20% for each against a control group receiving only the basal diet, within a period of 12 weeks. The effects of these different diets were evaluated on the weight of some target organs, the variation of body weight, the lipid profile and the arterial blood pressure.The intake of these oils led chronologically to growth retardation (31%); atherogenic dyslipidemia characterized by a highly significant increase of the atherogenic index (117%) and plasma level of total cholesterol (59%), triglycerides (200%) and LDL cholesterol (108%). However, a marked decrease in HDL cholesterol (79.9%) was also noted, with hypertension as a consequence for which an increase of 76.5% of the blood pressure was recorded in the group of animals receiving 20% RPO. A high intake of fresh or refined palm oil could probably cause growth retardation, atherogenic dyslipidemia and arterial hypertension.