ISSN: 2249-9504
CAS CODEN: IJPCDX

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Citations : 3566

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DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR QUANTITATIVE ANALYSIS VOGLIBOSE IN PURE AND PHARMACEUTICALFORMULATIONS

Abstract

Author(s): V.Sai kishore, P.Jitendrakumar*, T. Kalyan chakravarthy, S.Venkatesh Naik, M.Harshavardan Reddy and E.Nagarjuna Babu

A Validated simple, sensitive, specific and precise RP-HPLC method was developed for the determination of Voglibosein pure and pharmaceutical formulations. Method was carried on Zodiac C18 column(250mm×4.6mm×5μ particle size) using Methanol: Acetonitrile(75:25) as mobile phase.Detection was carried out by U.V at 215nm. The proposed method obeyed linearity in the range of 20-140 μg/mland met all specifications as per ICH guidelines. Statistical analysis revealed that this method can be used in routine quality control studies of Voglibose in pure and its formulations

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