ISSN: 2249–9504
CAS CODEN: IJPCDX

COUMARIN AS A VERSATILE SYNTHON IN MEDICINAL CHEMISTRY

Abstract

Author(s): Singh Sarbal and Goyal Anjali*

Coumarins are used for various biological activities from ancient times, recently researchers developed novel synthetic and semisynthetic coumarin based therapeutic agents. Molecular hybridization concept using different coumarins is used in the synthesis of many of these agents. The nucleophilic and electrophilic properties of coumarins make them potential candidates for substitutions and hybridization to synthesize new drug molecules. The present review shows the coumarin as a potent scaffold for the substitution and molecular hybridisation with other heterocyclic rings

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