ISSN: 2249–9504
CAS CODEN: IJPCDX

COMPARATIVE STUDIES OF CENTRAL NERVOUS SYSTEM DEPRESSANT ACTIVITY ON HYDROALCOHOLIC EXTRACT OF ACALYPHA INDICA AND CROTAN BONPLANDIANUM

Abstract

Author(s): P admaja Kota*, Keerthi Sammeta, Jagadeesh Panda,M. Uma Rani, R. vishna, K. Nagaraju

The whole plant extract of acalyphaindica and croton bonplandianum obtained cold extraction of mixture of ethanol and water was chosen for pharmacological screening.The Swiss albino mice are subjected to extract at 125 mg/kg to check the CNS depressant activity by actophotometer test. The test and standard were given orally. After 60 min. the animal are placed in to the actophotometer and observation were recorded at the interval of 90,120 and 180 min. acalyphaindica showed CNS depressant effect but crotonbonplandianum has no depressant activity.

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