ISSN: 2249–9504
CAS CODEN: IJPCDX

CHEMOSTERILIZATION INDUCED BY INTRATESTICULAR INJECTION OF CALCIUM CHLORIDE (CaCl2) - A TOOL FOR POPULATION CONTROL

Abstract

Author(s): Soumendra Nath Karmakar* and Shyamal Kanti Das

Present study evaluates the effect of intratesticular calcium chloride (CaCl2) injection on reproductive system of male albino rats. The effect has been observed on various reproductive parameters. Besides insignificant increment in body weight, the testicular weight and epididymal weight as accessory sex organ have been decreased significantly in dose treated groups. Sperm count and sperm motility have also been reduced significantly in experimental animals as the serum concentration of testosterone has also been drastically reduced. In response of that, FSH has been increased in both dose treated groups while serum concentration of LH is increased only in high dose treated groups. On the contrary metabolic parameters such as serum glucose and protein remain unaltered significantly but altering the serum cholesterol level significantly only in high dose treated group. Metabolic marker enzymes such as SGPT and SGOT have not been changed significantly in dose treated groups comparing to their respective control group. Histological structure of testis has been altered in experimental animals showing disintegrated seminiferous tubules and hampered spermatogenesis.

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