ISSN: 2249-9504
CAS CODEN: IJPCDX

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Citations : 3566

International Journal of Pharmaceutical, Chemical and Biological Sciences received 3566 citations as per google scholar report

International Journal of Pharmaceutical, Chemical and Biological Sciences peer review process verified at publons

CHEMICAL COMPOSITION, ANTIRADICAL AND ANTI-INFLAMMATORY ACTIVITIES OF FOUR ANNONACEAE FROM BENIN

Abstract

Author(s): Guy Alain Alitonou1*, Fidele Paul Tchobo1, Philipe Sessou1, FĂ©licien Avlessi1, Chantal Menut2 and Dominique CK. Sohounhloue1

The chemical composition of the essential oils obtained by hydrodistillation from fresh leaves of four Annonaceae:Annona muricata, Annona squamosa,Monodora myristica andXylopia aethiopicagrowing wild in Benin were analyzed by GC and GC/MS. Twenty four compounds were identified and quantified in the essential oil of Annona muricatawith isocaryophyllene (20.2%); caryophyllene (16.1%); cadinene (11.4%), elemene (8.9%); muurolene (6.9%) as major components. Twenty nine compounds were identified and quantified in the essential oil of Annona squamosawhich contained isocaryophyllene(24.9%), camphene (10.2%), caryophyllene (2.6%), epi-cadinol + epiuurolol (9.2%) as prominent components. Essential oil of Monodora myristicascreened contained twenty four components identified and quantified with phellandrene (65.5%), pinene (6.2%) as main compounds. Thirty three compounds were identified and quantified in the essential oils of Xylopia aethiopica,the major compounds being p-cymène(16.0%), sabinene(12.6%), terpinen-4-ol (11.3%), elemene (10.6%) and pinene(7.1%). The antiradical and anti-inflammatory activities of these oils were found to be low.

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