Abstract
Author(s): S. Bakkialakshmi*, G. Jayaranjani
Many recent reports on curcumin, a polyphenol from Curcuma Longa,provide mounting evidence on the pharmacological activity of this natural product. However,the pharmaceutical use of this molecule is hampered due to its poor solubility in the aqueous media,inclusion complex formation with cyclodextrins has been reported as a means to enhance its aqueous solubility. Most of the studies provide Infrared (IR) spectroscopic data as an evidence to support inclusion complex formation.In this study,fully water soluble complexes of curcumin with two β-cyclodextrins were isolated and characterized.