Author(s): Harikrishna Ramaprasad Saripalli1* and Prasanna Kumar Dixit2
The knowledge of plants as therapeutic agents is as old as disease, which in turn is as ancient as man himself. Since times immemorial plants have been in use to cure the human ailments. In traditional medicinal system, several plants have provided important cues for being used as potent bioactive compounds against various disorders and diseases causing organisms. al and Still number of plants has yet to be screened for their potential as medicinal plants. In accordance with this information, antimicrobial activities of plant were tested, which is commonly considered as traditional medicinal plant. Solvent extracts of leaves, fruit pulp and seeds of Graviola (Gishta) cultivar of Ethiopia made in petroleum ether, chloroform, ethanol, methanol were tested for antimicrobial activity against Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa, Corynebacterium diphtheria, Xanthomonas citrovorum, Proteus vulgaris, Staphylococcus aureus, Aspergillus niger, Aspergillus fumigatus and Candida albicans. The petroleum ether and ethanol extracts of seeds of Graviola or Gishta (Annona spp. of Ethiopia) shown increased zones of inhibition for the test bacteria Corynebacterium diphtheria, the fungal organism highly sensitive to methanol and chloroform extract was Asperigillus niger. The petroleum ether, chloroform and methanol extract of fruit pulp and leaves of Graviola or Gishta (Annona spp. of Ethiopia) shown increased zones of inhibition against fungal spp. The ethanol extract exhibited high activity against the growth of Corynebacterium diphtheria.The obtained results data statistacally analyzed and tested using a full factorial Analysis of Variance (ANOVA) model.