ISSN: 2249–9504
CAS CODEN: IJPCDX

ANTI INFLAMMATORY AND ANTI NOCICEPTIVE EVALUATION OF ROOTS EXTRACTS OF BAUHINIA PURPUREA LINN

Abstract

Author(s): NirmalaJane Pais*, Ullas Prakash D Souza,Prasanna Shama K andShastry CS

The present study was carried out to evaluate the anti nociceptiveactivity of the roots of theBauhinia purpurea Linn plant. The rats weighing around 150-200g were selected, the ethanolic extracts of dried roots of Bauhinia purpurea Linn were administered at following dose of 100, 200, 400 mg/kg body weight were used. The study was conducted as per the “Tail flick Method” and “Acetic acid induced writhing method”. Bauhinia purpurea Linn roots have shown significant Antinociceptiveactivity at 200 and 400 mg/kg in both the models, whereas 100mg/kg dose did not produce significant results when compared with control. (P<0.001) .The results of anti inflammatory activity of ethanolic extract produced significant results at doses of 200 & 400mg/kg (P<0.001) in “carrageenan induced paw edema model” and” cotton pellet Granuloma pouch method”. The findings indicated the Anti inflammatory & Anti nociceptive evaluation ofroot bark extract of Bauhinia purpureaLinn.

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