Abstract
Author(s): D. Anilkumar*, P. Sudarshan, K. Ragavan and M. Niranjan Babu
Artificial blood is a product made to act as a substitute for red blood cells, blood substitutes are used to fill fluid volume and/or carry oxygen and other blood gases in the cardiovascular system. More accurate terms are volume expanders for inert products, and oxygen therapeutics for oxygen-carrying products. It is required to overcome the Hypovolemic Shock During Accidents, Surgery Etc..,. Ideal blood substitute should have Universal compatibility: elimination of cross matching, Pathogen free, Minimal side effects, Survivability over a wider range of storage temperatures, Long shelf life, Cost efficient etc. Their main function is replacing lost blood volume and oxygen carrying capacity. Haemoglobin-based oxygen carriers vaguely resemble blood. Two major areas of research in this Endeavour are Hemoglobin-based oxygen carriers (HBOC) and per fluorocarbon -based oxygen carriers (PFBOC). These can reach tissues more easily than normal red cells and can delivery oxygen directly and extensive clinical trials are being conducted to their safety and efficacy.