ISSN: 2249–9504
CAS CODEN: IJPCDX

UV SPECTROSCOPIC METHOD FOR ESTIMATION OF LINEZOLID IN TABLETS

Abstract

Author(s): BH. Saikiran1*, SK. Johnny2and P. Leela madhuri2

A simple, sensitive, specific, and validated UV method has been developed for thequantitative determination of Linezolid in pure and tablet dosage form. The λmax was found to be 590nm for assay. The linearity was found in concentration range of 3-18 μg/ml. The correlation coefficient was found 0.999. The regression equation was found as Y= 0.030X + 0.006. The method was validated for linearity, accuracy, precision and ruggedness. The LOD and LOQ for estimation of Loperamide were found as 0.09784, 0.2951respectively. Recovery of Loperamide was found to be 96.93%.

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