ISSN: 2249-9504
CAS CODEN: IJPCDX

Abstracted and Indexed

open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing open access publisher, open access publishing, open access journals and articles, peer reviewed open access journals, insight medical publishing
+32 25889658
Google Scholar citation report
Citations : 3566

International Journal of Pharmaceutical, Chemical and Biological Sciences received 3566 citations as per google scholar report

International Journal of Pharmaceutical, Chemical and Biological Sciences peer review process verified at publons

SYNTHESIS, SPECTRAL STUDIES AND ANTIMICROBIAL ACTIVITY OF 8-METHYL-2-SUBSTITUTED-6H-CHROMENO [6,7-d] OXAZOLE-6-ONE DERIVATIVES

Abstract

Author(s): Damini Puri, Davinder Singh and Monika Gupta*

Antibiotic resistance has been a global healthcare problem due to the indiscriminate use of antibiotics and the subsequent creation of bacteria that can survive traditional treatment. Present research work focused to synthesis of coumarin derivatives. Figure 2 shows synthesis of compounds 8-Methyl-2-substituted-6H-chromeno [6,7-d] oxazol-6-one. All the Molecules were evaluated against Gram positive bacteria Staphylococus aureus (MTCC 3160), Gram negative bacteria E. Coli. (MTCC 614) for antimicrobial activity. The derivative bearing 2-chloro (6f) substituent possessed maximum activity against Gram negative and minimum activity against Gram positive bacteria, whereas 4-chloro (6d) substituent exhibited good activity against both strains.

Get the App