ISSN: 2249–9504
CAS CODEN: IJPCDX

SYNTHESIS, CHARACTERIZATION, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF ISATIN DERIVATIVES

Abstract

Author(s): R. Vasanthi1*,Y. Rajendraprasad2and H. Ramana

Heterocyclic compounds have a wide range of application in the field of chemistry. The fusions of several rings resulting in polycyclic structures from biologically active heterocyclic templates are always of interest to both organic and medicinal chemists. In view of these facts and continuation of our work on some pharmacologically active heterocyclic compounds by condensation of(3)-3-hydrazinylidine-1, 3-dihyro-2h-benzo (g) indol-2-one has been condensed with different thiadiazole derivatives. The chemical structures of synthesized compounds where confirmed by means of IR, NMR spectral data and compounds were screened for their antibacterial, antifungal activity.All the novel Isatin derivatives exhibited mild to moderate activity. Compound14 & 15 exhibited better activity than the other test compounds

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