ISSN: 2249–9504
CAS CODEN: IJPCDX

SYNTHESIS ,CHARACTERIZATION AND COMPUTATIONAL STUDY OF SOME NEW 5-(FURAN-2-YL)-3-PHENYL-4,5-DIHYDROISOXAZOLE DERIVATIVES FROM CHALCONE COMPOUNDS

Abstract

Author(s): Abbas F. Abbas, Nesreen N. Majeed and Afaq A. Turki

An efficient and practical synthesis of six compounds of isooxazoline derivatives was achieved through cyclization of hydroxyl amine hydrochloride with α,β--unsaturated ketones (chalcones) using glacial acetic acid as catalyst under thermal conditions. These compounds were characterized by using elemental analysis, FT-IR spectroscopy and 1H-NMR spectroscopy

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