ISSN: 2249–9504
CAS CODEN: IJPCDX

SYNTHESIS AND CHARACTERIZATION OF NEW 7-HYDROXY-4-METHYL COUMARIN INCORPORATED FLAVANONE AND ISOXAZOLINE DERIVATIVES

Abstract

Author(s): Swati A Gadkhe* and Anil B Naik

In the present study, new substituted isoxazolines (4a-c) have been synthesized via the simple and efficient reaction of flavanones (3a-c) with the hydroxyl amine hydrochloride in ethanol. The structures of the compounds were elucidated by elemental and spectral (IR, 1HNMR, and MS) analysis. The reactions are easy to conduct, under mild conditions, and form coumarin substituted flavanones and isoxazolines in moderate to excellent yields.

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