ISSN: 2249–9504
CAS CODEN: IJPCDX

PRONIOSOMES:A FUTURE REVOLUTIONARY DRUG DELIVERY SYSTEM

Abstract

Author(s): Sulthana AA*, BobyJohns George,Jeny Samuel, NobyThomas,Daisy PA and Betty Carla

The present article provides an insight to provesicular carrier system for various pharmaceutical and cosmeceuticalapplications. Vesicular drugdelivery reduces the cost of therapy by improved bioavailability of medication, especially in case of poorly soluble drugs. They can incorporate bothhydrophilic and lipophilic drugs. Approaches to stabilize niosomal drug delivery system without affectingits properties of merits have resulted in the development of promising drug carrier,proniosomes .These proniosomes minimize the problems of aggregation, fusion and leakage of drugs and provides additional convenience in transportation, distribution, storage and dosage. It prolongs the existence of drug in systemic circulation .Proniosomes are dry formulation of water soluble carrier particles that are coated with surfactants and can be hydrated to form a niosomal dispersion immediately before use by briefagitation in hot aqueous media

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