ISSN: 2249–9504
CAS CODEN: IJPCDX

OXIMES ESTERS AS POTENTIAL PHARMACOLOGICAL AGENTS ? A REVIEW

Abstract

Author(s): AS. Harikrishna*, K. Krishna Kumar and G. Elias

Numerous oxime derivatives have been synthesized and their biological activities were evaluated over the last several decades. Of all the oxime derivatives, oxime esters have been reported to hold more promise as potential therapeutic agents. Oxime esters are the group of organic compounds synthesized by condensation of aldoximes or ketoximes with carboxylic acids and include a large number of heterogenous compounds. Biological activities such as anti-oxidant, anti-microbial, antiinflammatory, anti-cancer and tranquilizer action have been reported for oxime esters of diverse chemistry. This review is intended to study the synthetic routes, chemistry and biological activities of the various oxime esters.

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