ISSN: 2249–9504
CAS CODEN: IJPCDX

METHOD DEVELOPMENT OF AN SIMULTANEOUS DETERMINATION OF COMMON COUGH AND COLD INGREDIENTS BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HLPC) IN MULTI COMPONENT COUGH AND COLD ORAL DRUG PRODUCTS

Abstract

Author(s): Sakshi Sawant1* and Nitin Borkar2

A common simultaneous HPLC method has been developed for the quantification of common analytes used in cough and cold products. The seven analytes acetaminophen, guafenesin, pheniramine maleate, phenylephrine hydrochloride, diphenhydramine, chlorpheniramine maleate, dextromethorphan are separated out. HPLC separation was achieved on a C18 column with a gradient system optimized for all seven analytes with different chemical structures.

Get the App