ISSN: 2249–9504
CAS CODEN: IJPCDX

METHOD DEVELOPMENT AND VALIDATION OF ELETRIPTAN HYDROBROMIDETABLETS BY UV-VISIBLE SPECTROPHOTOMETRIC METHOD

Abstract

Author(s): P. Sunitha*,CH.Jhansirani,B.Kavitha,N.Sirishaand A.Pavani

Simple, accurate, precise, linear and reproducible method was developed for the estimation of Eletriptan hydrobromide pharmaceutical dosage forms by UV-Visible spectrophotometric method. The stock solutions were prepared by using combination of ethanol and distilled water. The absorbance of Eletriptan hydrobromide was found to be at 221nm. The calibration curve was plotted in the concentration range of 1-10μg/ml. In tablets Eletriptan hydrobromide percentage purity was estimated to be 99.65%. The results of analysis were validated according to ICH guidelines and were found to be satisfactory. Hence, present studies give excellent method for the determination of Eletriptan hydrobromide tablets.

Get the App