ISSN: 2249–9504
CAS CODEN: IJPCDX

ISOXAZOLES: MOLECULESWITH POTENTIALMEDICINAL PROPERTIES

Abstract

Author(s): K. Ajay Kumar and P. Jayaroopa*

Isoxazole is a five membered heterocyclic compound having various pharmacological actions. The great interest associated with isoxazoles and their derivatives is based on their versatility as synthetic building blocks, their latent functionalities as enaminones, 1,3-dicarbonyl compounds, γ-amino alcohols, and β-hydroxy nitriles have been widely exploited for the synthesis of other heterocycles and complex molecules. This review paper comprises of up to date information on isoxazole analogs. More emphasis was given to critical discussion on the synthetic strategy of isoxazole derivative, their utility as building blocks in their transformation to more biologically potent molecules. Resultsof isoxazole derivatives and their substitutions effect on diverse biological activities also presented.

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