ISSN: 2249–9504
CAS CODEN: IJPCDX

INVESTIGATION OF WOUND HEALING ACTIVITY OF ETHYL ACETATE EXTRACT OF FLOWERS OF CALOTROPIS GIGANTEAN

Abstract

Author(s): SM. Patil, R. Saini

Calotropis gigantea is used in herbal medicine for the treatment of skin itches, as antiseptic for wound, expectorant, asthma, anti viral, antimicrobial and useful in leprosy scabies ring worms of the scalp activity. The objective of our study is to investigate the effect of wound healing activity of ethyl acetate extract of flowers of Calotropis gigantea in rats. The animals were treated with the ethyl acetate extracts of Calotropis gigantea (400mg/kg/day and 800mg/kg/day) topically. Healing was assessed by the rate of wound contraction, period of epithelialization. The plant showed a definite, positive effect on wound healing in rats.

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