Author(s): Nimmi K Thampi* , Boby Johns George, Jeny Samuel, Daisy PA and Betty Carla
Pulsatile Drug delivery systems are gaining a lot of interest as they deliver the drug at the right site of action, at the right time and in the right amount, as per the pathophysiological needs of the diseases, resulting in increasing patient compliance. A combination of floating, pulsatile and multiparticulate systems is now widely employed for the treatment of various diseases. Floating pulsatile beads release drug after a lag time with no release during floating in the stomach after which a burst release in the upper part of the g.i.t. so drugs can be delivered at right time, in right amount and at right site of action by use of floating pulsatile beads.