ISSN: 2249–9504
CAS CODEN: IJPCDX

EFFECT OF ENDOSULPHAN ON LACTIC DEHYDROGENASE ACTIVITIES IN THE VITAL TISSUES OF SWISSALBINO MICE

Abstract

Author(s): K.Joseph John*, M. Santhosh Mathews and K. Vimala John

Healthy adult female albino mice Mus musculus of Swiss strain were exposed to sub lethal concentration of 6 mg/kg body weight of endosulphan for 21 days, 60 days and 90 days respectively. The fluctuations of the variation in Lactic dehydrogenase (LDH) in brain,liver and kidney were estimated. In acute doses LDH increase in all tissues, whereas on subchronic and chronic period there was decreased trends.

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