ISSN: 2249-9504
CAS CODEN: IJPCDX

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Citations : 3566

International Journal of Pharmaceutical, Chemical and Biological Sciences received 3566 citations as per google scholar report

International Journal of Pharmaceutical, Chemical and Biological Sciences peer review process verified at publons

DIURETIC ACTIVITY OF CALOTROPISPROCERA(AIT.) R. BR. LEAVES IN NORMAL RATS

Abstract

Author(s): YogeshMurti*, Saurabh Sharmaand Pradeep Mishra

Calotropisprocera(Ait.) R. Br. (Asclepiadaceae), a xerophytic shrub widely distributed in the tropics of Asia and Africa, is used in various forms as panacea for diverse health problems in different parts of the world. In view of its medicinal importance, an ethanolic extract, water and n-butanol fraction of ethanolic extract of Calotropisprocera(Ait.) R. Br. leaves were investigated for in-vivodiuretic activity by using Lipchitz method. Results of diuretic activity showed that ethanolic extract and water fraction produced notable diuretic effect which appeared to be comparable to that produced by the furosemide. The increase in urine output was statistically significant at all the treatment levels

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