ISSN: 2249–9504
CAS CODEN: IJPCDX

DETERMINATION OF BIOLOGICAL ACTIVITIES AND ACIDITY AT DRUG ACTIVE SUBSTANCE IN SOME BENZIMIDAZOLE DERIVATIVES

Abstract

Author(s): Fatih Islamoglu* , Naciye Erdogan and Emre Mentese

Some benzimidazole derivatives as known drug active substance were evaluated for their biological activities such as antibacterial, antiviral and antifungal activities. In addition, acid dissociation constants (pKa) were determined experimentially with potentiometric titration method and theoretically with SPARC computer programme about state acidity for these six compounds.

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