Author(s): Rishi Pal,Mangal Sain Hooda,Anil Bhandari and Janardhan Singh
Acacia Senegal Willd(Leguminosae), known as Arabic gum tree. Its mature pods with seeds wereextracted using solvents of different polarities and explored for in-vitrofree radical scavenging activity. Preliminary assays of both extracts of AcaciaSenegalpod scavenges 1,1-diphenyl-2-picrylhydrazyl stable free radicals in concentration dependent manner. All studied extracts possess electron donating ability and reduce ferric ion to ferrous in a cell free system at pH-7.4. It has also been found from total antioxidant capacity as assessed by reduction of molybdate showed Acacia SenegalPod-hydro alcoholic to possess when compared to standard ascorbic acid equivalents per milligrams of the extracts. Pod hydro alcoholic extracts were found more effective when compared to Pod water extract in scavenging 1,1-diphenyl-2 picrylhydrazyl, reducing ferric ion and molybdate reduction in antioxidant capacity. The significant correlations exist between extract concentrations and percentage scavenging activity of radicals in all models. Results clearly indicate that Acacia Senegal Pod is effective free radical scavenger and chain breaking antioxidant.